Cannabis is the most widely abused illicit drug in the United States. In the last decade, cannabis use disorders have become more prevalent, 1 the potency of cannabis available in the U.S. has strengthened 1,2 and the proportion of substance abuse patients whose primary drug is cannabis has increased. 3 Additionally, current cannabis use is projected to increase in the next decade among aging baby boomers. 4 Given these developments, an improved multidisciplinary understanding of this significant U.S. public health problem is essential to guide treatment and prevention efforts. An important aspect of the cannabis problem for which epidemiologic information is lacking is cannabis withdrawal.
