Chunk #13 — RESULTS — Genetically informative research approaches and their limitations — Evidence for heritable influences on substance initiation and use
While it is well established that about 50-70% of the variation in alcohol use disorders is due to heritable factors,30 initiation of alcohol use is largely influenced by shared environmental influences, with a review by Hopfer et al31 indicating that in the region of 50-70% of variation in alcohol initiation could be attributed to shared environmental factors.
