Thus, to fill an important gap in public health knowledge related to the consistencies of the comorbid patterns of AUD, ND and mood and anxiety disorders across culturally diverse countries, especially of Asian countries, this study was aimed at comparing the prevalences and comorbidity of AUD, ND and mood and anxiety disorders between the United States and Korea. Two contemporary nationally representative surveys conducted in the United States (2001–2002) and South Korea (2001) provided a unique opportunity to address these questions.