The sample population was limited to European Americans and young adults. Recent drinking history was derived from a 30 day TLFB taken at time of enrollment; no assessment of longer term drinking history was included. A double-blind study was not possible due to the several BrAC measurements taken during the alcohol infusion that are employed as real-time feedback to the software computing individual infusion rate profiles in order to insure identical trajectories of alcohol exposure. However, the quality of the single-blind was maintained by acquiring BrAC readings with the same frequency during the placebo infusion as during the alcohol infusion, and the subject was not informed of the BrAC results in either session. In addition, session order (placebo vs alcohol in the first session) was not significant, and responses during the placebo session were accounted for in the statistical model.
