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Chunk #46 — Other Modalities

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Sex/gender differences in brain function and structure in alcohol use: A narrative review of neuroimaging findings over the last 10 years.
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women may have both behavioral and physiologic deficits related to alcohol consumption and inhibitory processing, whereas men only demonstrate physiologic deficits. Such findings may have implications for alcohol-related disinhibition in the development of AUD. Further, using ERP in an alcohol cue reactivity task, male binge drinkers exhibited greater P3 amplitude reactivity to alcohol cues vs. no-alcohol cues compared to male light drinkers; an effect not significant in women (Petit, Kornreich, Verbanck, & Campanella, 2013). This result suggests that binge drinking men may have greater alcohol cue reactivity compared to light drinkers and women, and this may be a possible mechanism by which men develop AUD. SG differences in behavioral inhibition and alcohol cue reactivity should be further investigated as it relates to ERP and other imaging modalities.