2 trans). Reducing the dataset further to exclude linked associations within haplotype blocks leaves 346unique cis and 10 unique trans associations at the stringent genome-wide 5% significance level. These proportions are in good agreement with most other GWAS expression studies on blood or lymphocyte cell lines16,17,23–26, and a 30-fold or greater excess of cis over trans associations is also supported by 1% FDR estimates of 600 and 20 genes respectively. Complete lists of peak cis and trans associations are provided in Supplementary Table 3 online.
