associated with alcohol problems (Zucker, 2008), and there is more modest evidence for a risk pathway characterized by internalizing symptomatology (Zucker, 2008; Hussong et al., 2011). Further, individuals with alcoholism also show considerable heterogeneity, with a common distinction being alcoholics who have antisocial/externalizing traits and alcoholics who have anxious/depressive comorbid features (Cloninger et al., 1981; Babor et al., 1992). These literatures all indicate that individuals who misuse alcohol are a heterogeneous group. Yet our current prevention/intervention strategies often apply a one-size-fits-all strategy that focuses almost entirely on alcohol use and not on the various factors that (differentially) affect risk.