In the past decades, we have made considerable progress in understanding the molecular mechanisms underlying nicotine addiction, which is largely due to the identification of various neurotransmitter receptors, genes or pathways associated with addiction and the development of animal or cell models. Additionally, with the development of high throughput analysis technology, more and more genes/proteins have been suggested to be linked to nicotine addiction and provide a valuable resource to analyze candidate genes function, biochemical pathways and networks related to nicotine addiction. In this study, we provided a comprehensive analysis of the functional features and interaction network of nicotine addiction-related genes.
