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Chunk #42 — Discussion

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Alcohol dependence and reproductive onset: findings in two Australian twin cohorts.
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For the most part, the effects of comorbid psychopathology on reproductive timing were also opposite in direction to AD, but consistent with research on psychiatric predictors of teenage childbearing (Kessler, Berglund, Foster, Saunders, Stang, & Walters, 1997). In the young cohort, CD was associated with earlier childbearing in women through age 24. For both women and men in the young cohort, CD was associated with delayed childbearing after age 24, but effects were non-significant. In both cohorts, a similar pattern was observed for history of MDD, suicide attempt, and panic attack in models where these variables were examined either as time-invariant or -varying predictor of reproductive onset. In the older cohort, MDD predicted earlier childbearing in women, but delayed childbearing in men after age 29. A pronounced effect of suicide attempt was observed for men through age 20. Although each is a well-documented predictor of future AD, family and childhood risk variables showing significant association with reproductive timing also predicted earlier first childbirth.