paperKB
coga / coga-kb
Help
Sign in

Chunk #14 — USE EXAMPLE

Source
HaploReg v4: systematic mining of putative causal variants, cell types, regulators and target genes for human complex traits and disease.
Embedded
yes

Text

Then go to the entry on the block for the lead SNP itself, rs864643. Click on the rsid, which is colored red because it is the lead SNP. Note that in the full table of epigenomic information from Roadmap Epigenomics (11), there is a cluster of enhancer activity in brain, and that it is classified as a genic enhancer by the 15-state core model and transcribed 3′ enhancer by the 25-state model (Figure 2). Note that H3K4me1, H3K27ac and H3K9ac all contribute to the chromatin state assignment at this locus. Black cells on the right hand of this part of the table indicate that DNase was not assayed by Roadmap in these tissues.