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Chunk #17 — 2. Methods — 2.6. Statistical analyses

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Two HPA axis genes, CRHBP and FKBP5, interact with childhood trauma to increase the risk for suicidal behavior.
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In order to prevent spurious G × E results due to small sample sizes, for each of the SNPs that had minor allele frequencies (MAF) of ≤0.30 the minor homozygotes and heterozygotes were combined as one group.