In all subjects, the regression for verbal memory identified the RD of the orbital frontal segment (B = −21.08; p = 0.013), the temporal segment (B = 13.97; p = 0.012), and the occipital segment (B = −10.96; p = 0.041) as predictive variable accounting for 34.5% of the variance (F = 5.96; p = 0.002). In the SZ group, the RD of callosal fibers in the occipital segment was significantly associated with the z‐score of verbal memory. The regression for verbal memory identified the RD of occipital segment as predictive variable accounting for 33.9% of the variance (B = −13.10; F = 8.74; p = 0.009). In the SZ group, the RD of callosal fibers in the posterior parietal and occipital segment was significantly associated with the scores of the PANSS general psychopathology and PANSS total. The regression for the PANSS general psychopathology identified the RD of posterior parietal segment (B = −398.75; p = 0.001) and occipital segment (B = 109.26; p = 0.010) as predictive variable accounting for 54% of the variance (F = 9.40; p =