Our method is also able to partition total narrow-sense heritability (h2) along genomic segments such as chromosomes, as we have shown by application to the phenotypes in the CARe data set. This is distinct from recent work that instead partitioned the heritability explained by genotyped SNPs (hg2) across chromosomes31-33. While a previous method has also partitioned h2 along chromosomes34,35, it relies on the use of siblings, leading to very large standard errors, and is limited by the coarseness of shared IBD segments (which extend for tens of megabases). Our approach is limited by the coarseness of local ancestry segments (which extend for megabases) and thus cannot be applied at the level of individual genes.
