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Chunk #29 — 3. RESULTS — 3.4 Multivariate twin models

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Genetic etiology of the common liability to drug dependence: evidence of common and specific mechanisms for DSM-IV dependence symptoms.
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familial effects on alcohol and tobacco in males and females, but limited familial effects on cannabis (more so in males (Δχ2 = 1.57, Δdf = 2, P = 0.45, ΔAIC = −2.43) than females (Δχ2 = 4.26, Δdf = 2, P = 0.12, ΔAIC = 0.26)). Model-wide tests of differences in the magnitude of substance-specific genetic and environmental effects between males and females indicated that the genetic and environmental effects specific to tobacco and alcohol could not be equated; however, there was evidence to suggest that cannabis-specific effects could be equated across genders.