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Chunk #22 — Results — Correlations between the TR and ReHo of Spontaneous Activity in the Whole Brain (Gray Matter)

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The Default Mode Network Supports Episodic Memory in Cognitively Unimpaired Elderly Individuals: Different Contributions to Immediate Recall and Delayed Recall.
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Voxel-wise correlation analyses showed that resting-state ReHo values correlated with AVLT-TR scores in a number of brain regions, most of which were located within the default mode network (DMN) (Table 2). The ReHo maps displayed very similar spatial patterns to the DMN proposed by a PET study by Raichle et al. (2001). Specifically, the ReHo values positively correlated with AVLT-TR scores in the posterior cingulate cortex/precuneus (PCC/PCu) and inferior parietal lobule (IPL), while negative correlations between the ReHo values and AVLT-TR scores were found in the medial prefrontal cortex (mPFC) and parahippocampal gyri (PHG) (Figure 1). In addition, using the data prepossessed with the MCALT, we replicated our results by finding significant correlations between the ReHo values and AVLT-TR scores within the critical DMN regions (i.e., the PCC/PCu, the IPL, and the PHG, all p < 0.01), except the mPFC. Therefore, the reliability of the main findings was confirmed with different templates.