Supplementary InformationThis file contains details about the TOPMed project and analyses described in the main text, complete list of additional authors from the TOPMed Consortium, grant acknowledgements for each author, acknowledgements and ethics statements for the contributing TOPMed studies. Reporting Summary Supplementary Tables and FiguresThis file contains Supplementary Tables 1-30 and Supplementary Figures 1-51 with their corresponding legends. Supplementary Data 1This spreadsheet contains table with between-cohort rare variant sharing values from Figure 4. Supplementary Data 2This file contains raw and normalized Singleton Density Scores (SDS) from the section on human adaptations.
