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Chunk #8 — Introduction — Development of Nicotine Use and Addiction

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The interplay of genes and adolescent development in substance use disorders: leveraging findings from GWAS meta-analyses to test developmental hypotheses about nicotine consumption.
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for the observed correlations among cigarette initiation, use and dependence and, more broadly, among substance use disorders. Adolescents initiate nicotine, alcohol, and drug use in part because they tend to act impulsively. Those who act more impulsively will be more likely to experiment with cigarettes and, once regular users, more likely to smoke more often, thus consuming more cigarettes per day.