using the box-counting software FracLac, representing the pixel mass distribution in microglia images. CHP is the single outline of the convex hull expressed in microns. CHA refers to the measurement of the area enclosed by the smallest convex polygon, which is defined as a polygon with all interior angles smaller than 180 degrees, encompassing the entire cell shape. CC was calculated as (4π × cell area)/(cell perimeter)2. The circularity value of a circle is 1. The convex hull span ratio is determined by calculating the ratio between the major and minor axes of the convex hull.
