We compared transcriptomic imputation accuracy in European and African-American individuals, and found that our models were applicable to either ethnicity with only a small decrease in accuracy. Common SNPs shared across ethnicities have important effects on gene expression, and as such we expect GREX to have consistency across populations. There is a well-documented dearth of exploration of genetic associations in non-European cohorts58,59. We believe that these analyses should be carried out in non-European cohorts.
