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Chunk #5 — Results — Overview of data generation, alignment and variant discovery

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A map of human genome variation from population-scale sequencing.
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A total of 4.9 Tb of DNA sequence was generated in nine sequencing centres using three sequencing technologies, from DNA obtained from immortalised lymphoblastoid cell lines (Table 1 and Supplementary Table 1). All sequenced individuals provided informed consent and explicitly agreed to public dissemination of the variation data, as part of the HapMap Project (see Supplementary Information for details of informed consent and data release). The heterogeneity of the sequence data (read lengths from 25 to several hundred base pairs; single and paired end) reflects the diversity and rapid evolution of the underlying technologies during the project.