Discovery phase analyses also included publicly available (via application) GWAS data from SAGE (http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000092.v1.p1), containing 1311 AA and 2750 EA unrelated individuals (Table 1). It is described in more detail in Supplementary Materials. A German sample of 1806 AD and 1978 control subjects was used for replication.9 Ordinal trait information was not available to us for these subjects, and the controls were not ascertained for exposure to alcohol and may include alcohol abusers.
