One emerging insight into the marijuana–panic relation is that it does not compare fully or similarly with that observed for cigarette use. Specifically, work has indicated that smoking rate for tobacco (cigarette use) is often significantly and robustly related to panic psychopathology (Zvolensky & Bernstein, 2005). The relation between marijuana use and panic psychopathology, on the other hand, is less robust and consistent (Bonn-Miller et al., in press). Moreover, the associations between the two forms of substance use in terms of panic psychopathology likely involve different mechanisms. It is difficult to draw firm conclusions in this domain, as work has emerged only in the past few years One important area of future work, especially considering the high rates of co-occurrence between marijuana and tobacco use (Fergusson, Horwood, & Swain-Campbell, 2002), will be to compare in one model the individual and interactive effects of marijuana and tobacco use in relation to panic psychopathology across time and the mechanisms underlying each association.