parietal areas associated with somatosensory function. Furthermore, these parietal projections follow the same somatotopic organization.73 Thus, the dorsolateral striatum is linked to motor function.71 Physiological studies support this idea, demonstrating somatotopic maps and neuronal responses to specific movement.74,75 Moreover, imaging studies in humans show that activity in the lateral putamen is associated with repetitive and well-learned movements that require little cognitive effort. In contrast, activity recorded during the learning of sequential movements in both monkey physiological experiments, as well as in human imaging studies, demonstrate activity in the rostral motor regions (pre-supplementary motor area [SMA]) and more anterior striatal areas including the caudate nucleus.76,77 The frontal eye fields send projections to the striatum that terminate in the central lateral part of the head and body of the caudate nucleus. This area of the cortex also contains a rostral region, referred to as the supplementary eye fields, which has a relationship to the frontal eye fields, with respect to learned acquisition of oculomotor behaviors, similar to that which the rostral and caudal motor regions have to learned behavioral sequences of hand movements. 78 Finally, the motor cingulate cortex also sends an overlapping projection to the sensorimotor region of the striatum.71,79 Taken
