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Chunk #0 — Methods

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Comorbidity of severe psychotic disorders with measures of substance use.
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The Genomic Psychiatry Cohort (GPC) program is a multi-institutional collaboration 23. This resource includes a NIMH managed repository of genomic samples and detailed clinical and demographic data for investigations of schizophrenia and bipolar disorder. The current sample consists of 9,142 individuals with either the diagnosis of schizophrenia, schizoaffective disorder, or bipolar disorder with psychotic features, and 10,195 population controls. Individuals with bipolar disorder without psychotic features represented a relatively small subgroup (n=621) and are therefore not included in these analyses.