A series of repeated exposures of SH-SY5Y neuroblastoma cells to binge-drinking levels of ethanol over 3 weeks (CIE) led to changes in the expression of many genes, although most changes were of small magnitude (Supplementary Table S1). These fell into a number of pathways relevant to neuronal cells, many of which have been shown to be affected in the brains of animals exposed to CIE. Perhaps surprisingly, nearly all of the changes returned toward control levels after only 24 h without ethanol.
