In summary, the current study demonstrates the utility of a large general cohort with EHR-derived multiple independent measurements for studying BP genetics; it is reassuring that the same BP loci found in research-based cohorts are captured with high significance, and also that the longitudinal data typical for EHRs provide important opportunities for novel SNP discovery. The new SNPs found here may provide novel mechanistic insight into the control and treatment of hypertension, ultimately preventing a variety of clinical sequelae.
