To view the impact of the ELOVL7 SE event in the brain, we analyzed the associations between the genotype-imputed PSI (\documentclass[12pt]{minimal} \usepackage{amsmath} \usepackage{wasysym} \usepackage{amsfonts} \usepackage{amssymb} \usepackage{amsbsy} \usepackage{mathrsfs} \usepackage{upgreek} \setlength{\oddsidemargin}{-69pt} \begin{document}$${{{\hat{\mathrm \Psi }}}}$$\end{document}Ψ^) and brain volumes from UKB. We found that the SE contributed to changes of gray matter volumes in multiple regions involved in processing auditory and visual information, such as the left and right Heschl’s gyrus and left occipital cortex (Fig. 4 and Supplementary Table S7). This result shows that the ELOVL7 SE may impact specific brain regions, including the visual cortex which plays a role in alcohol addiction [64, 65].
