Fransson et al. (Fransson et al., 2010) used measures of degree and betweenness centrality to identify the location of network hubs in voxelwise networks in infants and adults, in a manner similar to recent studies in adults (Buckner et al., 2009; Sepulcre et al., 2010). As shown in Figure 6, the locations of hubs identified using either degree or betweenness centrality were quite similar within cohorts, but differed substantially between cohorts. In adults (Figure 6C,D), many hubs appear to lie in the DMN, whereas in children (Figure 6A,B), many hubs appear to lie in or near primary sensorimotor cortex. It is not immediately obvious why such close correspondence should exist between measures of degree and betweenness centrality, though similar findings have been previously reported (Buckner et al., 2009). Degree is a property of a single node regardless of its position in a network, whereas node betweenness centrality is highly dependent upon a node’s location within the network structure (e.g., two nodes of identical degree can have very different betweenness centralities if one is locally embedded within a module and the
