Regarding Hypothesis 2, contrary to our projection of a decreasing relationship of SRE scores with recent drinking parameters as subjects age, the reverse pattern was observed. For SRE5, the correlations with past five-year alcohol quantities, problems and AUD diagnoses were more, rather than less, robust at T30 than at T15. Increases in correlations from T15 to T30 were also observed for SRET, and the relationships with drinking parameters were higher for the total SRE than for SRE5. This differential may relate to the fact that SRET considers more time points than SRE5, including the recent three-month period which might have partially reflected recent acquired tolerance for some subjects. While Hypothesis 2 also projected a decrease across time for relationships of the SRE to the alcohol challenge LR values from T1, those correlations were actually higher at T25 and T30 than at T15.
