outpatients with schizophrenia during a simple auditory oddball task (Garrity et al., 2007). In that study, unlike in ours, ventromedial PFC and anterior cingulate cortex were more coherent with the DMN in schizophrenia than in control subjects. There are many differences among these studies, including those in data acquisition details (TR, TR, voxel size), statistical approaches (seed-based functional connectivity, ICA, other temporal homogeneity approaches), patient population (acute inpatient vs. outpatient), and task instructions (cognitive tasks vs. rest). In addition, many studies do not account for the potential effects of psychotropic medications on BOLD signal oscillations. It is clear that functional integration across nodes of the DMN is deficient in schizophrenia but methodological differences preclude further conclusions.
