due to the known role for BAF53b in post mitotic embryonic development. We developed two independent lines of CaMKIIα-BAF53bΔHD. Both lines have normal brain morphology (Supplemental Fig. S1A), but are characterized by significantly different levels of transgene expression in hippocampal tissue (BAF53bΔHDhigh and BAF53bΔHDlow; Fig. 1B), which is relevant to the hippocampus-dependent experiments in this study. Wildtype BAF53b levels and localization are unaltered in the BAF53bΔHD mice (Fig. 1C & Supplemental Fig. S1B-D).
