SNP not meeting the cut-off for follow-up would attain a noteworthy significance level when combining results from the discovery and replication samples. Phase 1 and 2 results were combined within population groups by meta-analysis. In Phase 3, we selected for replication 76 SNPs (Sympcountadj, N=44 and case-control, N=28, including 58 unique SNPs) with p<10−4 in either population in the Phase 2 analyses.
