Total information curves are shown in Fig. 3. Both alcohol and cannabis show increased information across the entire trait as additional criteria are included, with cannabis criteria providing information on the higher end of the trait. For heroin, the region along the trait measured with high information widened as additional criteria were added. The total information for cocaine associated with just the dependence criteria exhibited a large spike near the mean (=0) of the trait and information decreases in that region as additional criteria were added. Total information area (TIA) and 95% CIs are shown in Table 4. Adding craving alone to the dependence criteria did not significantly increase the total information for any substance. Adding abuse to dependence criteria significantly increased total information for alcohol. The combined addition of abuse and craving significantly increased the information for alcohol, cannabis and heroin, but not for cocaine.