Chunk #19 — Results — Subgroup Analysis

Source

Comorbidities in Obsessive-Compulsive Disorder Across the Lifespan: A Systematic Review and Meta-Analysis.

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Figure 3.1–3.36 in Supplementary File 4 shows figures depicting the results of the meta-regressions, for each comorbidity. Significant associations are presented in Figures 4–7. Significant effects of AAA were found for MDD (higher AAA, higher MDD), GAD (higher AAA, lower GAD), panic disorder (higher AAA, higher panic disorder), psychotic disorder (higher AAA, lower psychotic disorders), and substance use disorders (SUDs) (higher AAA, higher SUD)]. Significant effects of AOO were found for GAD (lower AAO, higher GAD), post-traumatic stress disorder (PTSD) (lower AOO, higher PTSD), agoraphobia (lower AOO, higher agoraphobia), body dysmorphic disorder (BDD) (lower AOO, higher BDD), ODD (lower AOO, higher ODD), and personality disorders (higher AOO, higher personality disorders). Y-BOCS total score, representing OCD severity, was significantly associated with lower rates of comorbid panic disorder (higher Y-BOCS, lower comorbid panic), tic disorders (higher Y-BOCS, lower comorbid tics), any OCRDs (higher Y-BOCS, lower OCRDs), anorexia nervosa (higher Y-BOCS, lower anorexia nervosa), and OCPD (higher Y-BOCS, lower OCPD). Percentage of male gender within the sample was associated with higher prevalence of any psychiatric comorbidity, bipolar disorder, psychosis, agoraphobia, specific phobia, ADHD, and ODD.