markers of risk. The electrophysiological imbalances in excitation–inhibition observed in the offspring of alcoholics may be involved in the predisposition to develop alcoholism (Begleiter and Porjesz 1999). Long-term studies of childhood and adolescent precursors of adult alcohol abuse consistently identify a cluster of behavioral traits described as disinhibited, undercontrolled, impulsive, or aggressive, which significantly predict high levels of alcohol consumption or abuse.