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Chunk #29 — Results

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A new statistic to evaluate imputation reliability.
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Although IQS can serve as an effective filter to minimize the use of poorly-imputed SNPs, the computation of IQS requires a sample that was both imputed and genotyped for the SNPs of interest. This is impractical in most situations. A secondary goal of this paper is to determine whether there are ways to evaluate imputation quality without knowing the true genotypes.