Chunk #8 — Methods — Study design and participating studies

Source

Genetic risk factors for ischaemic stroke and its subtypes (the METASTROKE collaboration): a meta-analysis of genome-wide association studies.

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Stroke was defined as a typical clinical syndrome with radiological confirmation. Stroke subtyping was done with the Trial of Org 10172 in Acute Stroke Treatment (TOAST) classification system.18 Where subtyping was done, brain CT or MRI was undertaken for more than 95% of cases in all the discovery cohorts.