(X2(1) < .01, p = .96), or FU2 (X2(1) = .14, p = .70). In assessing the main effects of ALDH2 genotype, as well as effects of moderation by parental alcohol use and misuse, and peer deviance, all 300 genotyped participants who had ever had a drink by the time of their latest assessment were included in the analyses of all compared models. However, in assessing the potential moderating effect of elder sibling alcohol use and misuse, analyses included only the 165 genotyped participants for whom elder sibling data were available.