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Chunk #14 — Method — Statistical Analysis — Drug-free state analyses

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Evaluation of genetic variability in the dopamine receptor D2 in relation to behavioral inhibition and impulsivity/sensation seeking: an exploratory study with d-amphetamine in healthy participants.
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We assessed stop and go RTs for differences between genotypic groups without administration of drug (placebo), using a one-way analysis of variance (ANOVA). We repeated the same analysis for the Impulsivity/Sensation Seeking subscale of the ZKPQ. We assessed the significance of each SNP for each phenotype after adjusting for multiple testing (12 SNPs) while accounting for the correlations between SNPs.