essentially a superset of the sample used here and that is approximately twice as large, did not obtain any genome-wide significant findings (McGue et al., 2013). Does this imply that the EEG endophenotypes we examined are better situated to detect individual variants? This is impossible to know without replication and meta-analysis, as well as a better understanding of the variants we did identify. However, the cost of collecting most psychophysiological measures may prohibit the kinds of sample sizes required, including for replication studies (de Geus, 2010)
