Modelling Transcription Levels from Histone Modification and TF-Binding PatternsPanels A and B show the correlative models between either histone modifications or TFs, respectively, and RNA production as measured by CAGE tag density at TSSs in K562. In each case the scatter plot shows the output of the correlation models (x-axis) compared to observed values (y-axis). The bar graphs show the most important histone modifications (A) or TFs (B) in both the initial classification phase (upper bar graph) or the quantitative regression phase (lower bar graph), with larger values indicating increasing importance of the variable in the model. Further analysis of other cell lines and RNA measurement types are reported elsewhere59,79.
