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Chunk #0 — INTRODUCTION

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Alcohol and Mortality: Combining Self-Reported (AUDIT-C) and Biomarker Detected (PEth) Alcohol Measures Among HIV Infected and Uninfected.
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Unhealthy alcohol use carries a risk of adverse health and social consequences and is a major public health issue.1,2 It is common among individuals infected with HIV (HIV+) and/or hepatitis C virus (HCV+) and may be particularly detrimental in these populations.3–6 The potentially high susceptibility to harm from unhealthy alcohol use may be related to its known association and negative impact on HIV medication adherence,4 disease progression,7,8 risk of hepatic disorders,3,9 and exacerbation of other effects of HIV infection.7,10 Unhealthy alcohol use is linked to harmful health consequences and mortality.9–12 A clear dose-dependent relationship between levels of heavy drinking and all-cause mortality has been reported.12,13