Gibbons and Mann used pooled data from 17 randomised controlled trials sponsored by Pfizer to examine neuropsychiatric adverse events associated with varenicline.10 Our study included industry and non-industry sponsored trials and more than twice the number of trials that they included. Their findings of no increased risk of suicidal events, depression, and agitation are consistent with our study. Although the authors did not include references to the published literature for their included studies (which made cross referencing difficult), it is likely that we included most of their studies in our analysis.
