An earlier study that offered a nicotine inhaler, bupropion SR, or a combination of both for 12 weeks to smokers wishing to stop smoking (Croghan et al. 2007) observed that smokers assigned to the combination therapy were more likely to be abstinent than those assigned to individual therapies. However, this study also showed that the smoking abstinence rate for minority smokers was significantly lower than that of the white smokers. The purpose of this current report is to analyze the study data as they relate to minority smokers enrolled in the open-label phase of this study.