ascertained only dichotomous disease traits, avoiding anthropometric traits such as height. To produce reliable replicability estimates across ancestries we included in our analysis the 28 diseases for which two or more GWAS were available in any of the two ancestral groups and at least one in the other group (e.g. 11 GWAS for lung cancer in Europeans and 5 in East Asians; 4 GWAS for Kawasaki Disease, 1 in Europeans and 3 in East Asians). Finally, we also added GWAS performed upon individuals of African ancestry for any of the 28 selected diseases.
