We have continued to update evidence for target–disease associations through routine releases from our data providers, as well as additional experimental evidence generated through Open Targets projects (such as Project Score) and the statistical genetics analyses from the Open Targets Genetics Portal. This has included clinical trial and drug target information for COVID-19 to aid in the effort to identify targets for the repurposing of existing drugs or development of novel treatments to help fight the pandemic. We have reviewed and reiterated our scoring of evidence, and enhanced the prioritisation of targets for particular diseases with the addition of tractability and safety information generated through Open Targets informatics projects. We are implementing a redesign of the Portal infrastructure, data pipelines and frontend to enhance usability and allow for more complexity in the data for the future.
