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Chunk #56 — Materials and Methods — Spring-embedded graph theoretic layout and visualization

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Functional brain networks develop from a "local to distributed" organization.
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yes

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then iteratively adjusts the positions of each node to reduce the total energy of the system to a minimum. As the pair-wise connections relax to their lowest energetic states the “natural” configuration of the network is revealed. By observing multiple “spring embedded” graphs across the subjects in age-order, approximately representing a 6 month temporal sliding box car (i.e., group1: subjects 1–60, group2: subjects 2–61, etc.), a movie representation can be made that shows the development of the full system (see Video S1). The interpolations, algorithm application, and movie production were performed using MATLAB (The Mathworks, Natick, MA) and SoNIA (Social Network Image Animator) [94].