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Chunk #4 — Methods

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Linkage analysis and association analysis in the presence of linkage using age at onset of COGA alcoholism data.
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where λ0(t) is the unspecified baseline hazard function, and Xj is a vector of observed covariates for the jth sib and β is a vector of regression parameters associated with the covariates. Zj is the unobserved genetic frailty. The genetic frailty is defined as the following