The TEMPS-A was administered to 1,263 of the 1,566 Wave 5 bipolar subjects that were genotyped as part of the BiGS sample. Although each of the 1,263 subjects had complete data for at least one of the subscales, an average of 1,176 subjects (range 1,172–1,185) were available for the analysis of each temperament based on complete subscale data due to the presence of missing data for individual questions. The TEMPS-A includes a total of 109 self-rated true/false questions (110 for women) designed to assess hyperthymic, dysthymic, cyclothymic, irritable, and anxious temperaments with 21 questions specific to each temperament subscale and 26 for the anxious subscale (24–25). The TEMPS-A has been shown to have very good reliability and internal consistency with the temperaments showing good stability over time (27–30).
