internal and external capsules, and superior corona radiata (see Fig. 2) (McQueeny et al. 2009). Functional consequences of adolescent heavy drinking are seen in attenuated frontal cortex response during spatial working memory (Tapert et al. 2004), and deficits on neuropsychological measures of attention (Tapert and Brown 1999), information retrieval (Brown et al. 2000), and visuospatial functioning (Tapert et al. 2002), with some studies showing sustained effects into adulthood (Brown et al. 2008). Drinking so much that hangover or withdrawal symptoms are experienced is associated with decreased performance over time (Tapert et al. 2002).
